Effectiveness evaluation of the ICE (Italian institute of foreing trade) promotional programme: case study

Evaluation and monitoring approaches and methodologies are spreading within the national and regional administrations directly involved in the management of the programmes co-financed by Structural Funds as well as within other institutional contexts where public policies are planned and implemented. The purpose of the present paper is to illustrate some results from a still ongoing training and consultancy project, on behalf of the ICE (Foreign Trade Institute), aiming at integrating ICE programming with evaluation and monitoring practices. Indeed, during the last year the ICE Programming Unit has been engaged in training and consultancy activities involving the application of evaluation and monitoring methodologies to the activities promoting ICE. The recipients of such initiative belong to the ICE Programming and Control Unit and they already gained experience in the evaluation area in the past within ad hoc working groups. More specifically, the purpose of this activity is to provide the opportunity to develop the means for a more effective management of the projects and start a broader process leading to organizational change and improvement.programme evaluation, effectiveness measure, customer satisfaction

The competitive repositioning of automotive firms in Turin: innovation, internationalisation and the role of ICT

Following the increasing competitive pressure and the emergence of new industrial poles within the auto industry, Italian firms have been the protagonists of an intense reorganisation, which is still ongoing. This case-study involves 13 supplier firms, operating in the automotive industry, localised in Turin, that have adopted a series of strategies aimed at improving their international competitiveness. The empirical findings show that there is a particularly strong innovative drive for the interviewed firms to position themselves in activities with greater added value and to undertake internationalisation strategies, from the 'lighter' to the more 'complex' forms, coupled with a use of information and communication technologies epresents a case of excellence.Innovation, Internationalisation, ICT, Automotive Industry

The Natuzzi Group and the Bari-Matera (Italy) upholstered furniture district. A case study of internationalisation in a traditional industry

The case-study focuses on the strategies adopted by the Natuzzi Group, world leader of the upholstered furniture sector, located in the Bari-Matera district (Southern Italy), to face increasing global competition and on their effects. In particular we consider the modes and determinants of productive internationalisation, carried out since 2000 by Natuzzi in China, Brazil and Romania to produce middle-low end products. By improving the competitiveness of the price-sensitive segment, the strategy contributed to the successful expansion of the Group until 2002. However, high range products, manufactured in Italy, record decreasing sales especially on the US market, despite the companys efforts in R&D and marketing and its investments in information technology. Moreover, due to Natuzzi's considerable weight in the district, the Groups performance impacts on the network of subcontracting firms, where a restructuring process is underway, raising questions about the evolution of the district.Internationalisation, Industrial District, Subcontracting

The Impact of Loyalty and Equality on Implicit Ingroup Favoritism

Extending recent investigations into the malleability of implicit ingroup favoritism, three experiments examined the role of indirect activation of equality and loyalty. Results showed that priming equality decreased implicit favoritism, measured through the Implicit Association Test and Go/No-Go Association Task, whereas priming loyalty enhanced it; spontaneous behavior (seating distance) was similarly influenced. A boundary condition was observed, namely change of intergroup setting: the effects of priming equality and loyalty ceased when these were primed after an irrelevant ingroup identity was made salient. In general, implicit favoritism can be reduced or increased after the activation of equality and loyalty respectively, and this underlines the importance of tackling discrimination by both lessening its expression, and removing factors that exacerbate it

A thermodynamic study on the interaction between RH-23 peptide and DMPC-based biomembrane models

Investigation of the interaction between drugs and biomembrane models, as a strategy to study and eventually improve drug/substrate interactions, is a crucial factor in preliminary screening. Synthesized peptides represent a source of potential anticancer and theragnostic drugs. In this study, we investigated the interaction of a novel synthesized peptide, called RH-23, with a simplified dimyristoylphosphatidylcholine (DMPC) model of the cellular membrane. The interaction of RH-23 with DMPC, organized either in multilamellar vesicles (MLVs) and in Langmuir-Blodgett (LB) monolayers, was assessed using thermodynamic techniques, namely differential scanning calorimetry (DSC) and LB. The calorimetric evaluations showed that RH-23 inserted into MLVs, causing a stabilization of the phospholipid gel phase that increased with the molar fraction of RH-23. Interplay with LB monolayers revealed that RH-23 interacted with DMPC molecules. This work represents the first experimental thermodynamic study on the interaction between RH-23 and a simplified model of the lipid membrane, thus providing a basis for further evaluations of the effect of RH-23 on biological membranes and its therapeutic/diagnostic potential

La Rete Ecologica Toscana: aspetti metodologici e applicativi

Interventions that can reduce the loss and the fragmentation of ecosystems are very important in the sphere of biodiversity conservation policies applied to areas of high human activity. Ecological networks, on a di erent scale, are important analytical and design tools, and they can highlight sources of biodiversity with the intention of ecological unification. The Tuscany Ecological Network project, based on habitat sustainability models and converted into a planning tool for the landscape plan of Tuscany, has underlined the need to pursue the objectives of biodiversity conservation within a landscape or extended area. The project approaches across the board sectoral policies in urban planning and infrastructure in the agricultural, forestry, and protected areas

Cross-talk between chronic lymphocytic leukemia (CLL) tumor B cells and mesenchymal stromal cells (MSCs): implications for neoplastic cell survival

Leukemic cells from Chronic Lymphocytic Leukemia (CLL) patients interact with stromal cells of the surrounding microenvironment. Mesenchymal Stromal Cells (MSCs) represent the main population in CLL marrow stroma, which may play a key role for disease support and progression. In this study we evaluated whether MSCs influence in vitro CLL cell survival. MSCs were isolated from the bone marrow of 46 CLL patients and were characterized by flow cytometry analysis. Following co-culture of MSCs and leukemic B cells, we demonstrated that MSCs were able to improve leukemic B cell viability, this latter being differently dependent from the signals coming from MSCs. In addition, we found that the co-culture of MSCs with leukemic B cells induced an increased production of IL-8, CCL4, CCL11, and CXCL10 chemokines.As far as drug resistance is concerned, MSCs counteract the cytotoxic effect of Fludarabine/Cyclophosphamide administration in vivo, whereas they do not protect CLL cells from the apoptosis induced by the kinase inhibitors Bafetinib and Ibrutinib. The evidence that leukemic clones are conditioned by environmental stimuli suggest new putative targets for therapy in CLL patients

Non-indigenous polychaetes along the coasts of Italy: a critical review

Non-indigenous species (NIS) represent one of the most relevant threats to biodiversity, ecosystem functioning and human activities, and their occurrence and spread have been the subject of numerous works and revisions. However, the information available is rather confused for several taxa, including polychaetes, which are characterised by having a high number of cryptogenic and questionable species. This work aims at providing a revised checklist of alien polychaetes occurring along the coasts of Italy, based on the examination of newly collected and deposited material and on the critical analysis of published and gray literature, and whenever possible on the re-examination of historical material. Of the 86 polychaete species reported as NIS in Italian waters, 25 are confirmed as alien species, while 3 are cryptogenic, and 40 should be considered questionable. Finally, 18 species were excluded from non-indigenous species checklists, either because they are native, or because they represent misidentifications of other species. The high number of cryptogenic and questionable species points at the need of molecular studies and taxonomic revisions for the majority of polychaete taxa reported as NIS, in order to clarify their taxonomy, origin, introduction pathways and spreading patterns